Early-onset colon cancer. Rising breast cancers in younger women.
Different tissues. Same signal.
Environmental exposures leave epigenetic fingerprints— seen in both breast and colorectal cancers.
An invisible imprint…that may shape disease decades later.
https://charlottekupewasserphd.substack.com/p/the-invisible-imprint-of-everyday
People will never understand the ongoing torture/torment of psych med withdrawal. This is pain you cannot even imagine or conceive of. Count yourself lucky and if you haven't experienced it.
Another horrible example of a lack of informed consent by the medial establishment and big pharma ...
Akathisia: the hidden risk of psychiatric medication, by @MaryanneDemasi https://open.substack.com/pub/maryannedemasi/p/akathisia-the-hidden-risk-of-psychiatric?utm_campaign=post-expanded-share&utm_medium=web
As always, excellent coverage here on this topic--and many others.
R to @MaryanneDemasi: If a drug can induce physical dependence and withdrawal, then a plan for stopping it should be part of the prescription.
LINK: https://blog.maryannedemasi.com/p/akathisia-the-hidden-risk-of-psychiatric
@MaryBowdenMD @ACE_CoalitionEd
@angpeacock1111 @atomicaceso @RPurssey
💊Akathisia: the hidden risk of psychiatric medication
As cases like @jordanbpeterson’s draw attention, longstanding questions about withdrawal, suicidality, and tapering can no longer be sidelined.
@MikhailaFuller @markhoro @LauraDelano
@jeffreytucker @DowdEdward @newstart_2024
@RepLuna @JDaviesPhD @DrSyedHaider
Perhaps next time you could ask him for data on the fate of the DNA byproducts present in the mRNA vaccines. We would also appreciate regulatory guidance on mRNA vaccine manufacturing especially as it relates to LNP-encapuslated DNA limits in mRNA vaccines.
https://charlottekupewasserphd.substack.com/p/they-acknowl
People often find it impossible to believe that a psych med— and/or withdrawing too fast from one— could lead to *years* (yes, years!) of profound disability.
For so many of us, it takes having direct personal experience to really grasp this stark and all-too-common reality.
“(This) may steady the ship, but it also begs the question: if the same structures remain, and similar leadership is chosen to run them, what is actually changing?” asks Dr @MaryanneDemasi
Are we really going to pretend to be alarmed and amazed that every day people are suddenly questioning the entire vaccine regime? It’s absurd. People are blaming RFK but this would have happened with or without his leadership on this issue.
Let’s Talk About Polling Methodology https://www.theepochtimes.com/opinion/lets-talk-about-polling-methodology-6013511?utm_source=ref_share&utm_campaign=twitter&rs=SHRNCMMW via @epochtimes
🎙️Retsef Levi reveals what unfolded inside ACIP before it was brought to a halt
An insider account of internal tensions, contested decisions, and the questions that were never resolved. https://blog.maryannedemasi.com/p/retsef-levi-reveals-what-unfolded @RetsefL
R to @MaryanneDemasi: FULL Interview
https://blog.maryannedemasi.com/p/retsef-levi-reveals-what-unfolded @RCR_NZ
• Inside the cancelled ACIP meeting
• How the process really works (and who shapes it)
• Legal pushback over vaccine injury
• “Utterly broken” system for recognising harm
• The leaked document — and what it shows
• Unanswered questions on DNA fragments
• Covid death reports in children
• Trust, pressure, and a system under strain
Jan 11, 2020: Chinese scientists publish the genetic sequence of SARS-CoV-2.
Jan 13, 2020: Moderna and NIH design the vaccine sequence within 48 hours.
Feb 24, 2020: Moderna ships the first batches of its mRNA-1273 vaccine to NIH for clinical testing.
Mar 16, 2020: The first participant is dosed in a Phase 1 trial.
No corners cut? Hardly. Animal and human studies were run in parallel.
Historical example of how vaccine mandates can backfire:
In 19th-century Britain, they raised uptake at first under threat of punishment, but later fuelled resistance and falling compliance in some communities.
Post-Covid, similar fractures in trust and compliance now emerge.
@jeffreytucker
Sick Care, working exactly as designed.
R to @MaryanneDemasi: It’s part of a familiar pattern in medicine: a steady expansion of who counts as “unwell” — and who ends up on drug treatment.
LINK: https://blog.maryannedemasi.com/p/the-blood-pressure-trap-medicine
@MaryBowdenMD @Fynnderella1
Quietly, but significantly ACIP’s charter has been rewritten.
It now explicitly includes:
• Review of vaccine safety gaps
• Consideration of adverse effects
• Ongoing scrutiny of mRNA platforms
That’s a meaningful shift in how decisions will be made going forward. Let’s hope help is on the way ❤️🩹😢
Link is in her comments 🔗
R to @MaryanneDemasi: For now, ACIP remains in limbo. But when it is reconstituted, its scope will be broader, its definition of expertise wider, and the expectations guiding its decisions clearer.
LINK: https://blog.maryannedemasi.com/p/breaking-acip-charter-rewritten-sweeping
BREAKING: ACIP charter rewritten — sweeping changes reshape vaccine advisory panel, by @MaryanneDemasi https://open.substack.com/pub/maryannedemasi/p/breaking-acip-charter-rewritten-sweeping?utm_campaign=post-expanded-share&utm_medium=web
🎙👋 We’re thrilled to welcome RCR's newest host: Maryanne Demasi 🇦🇺
Maryanne @MaryanneDemasi is an investigative journalist and medical scientist in Australia, whose work explores how scientific evidence becomes public health policy 🧬📊.
“My aim is to follow the evidence wherever it leads and show what’s really happening behind the scenes in public health.”
Keep your ears open — her first RCR episode drops soon! 🎧🌟
http://www.RCR.Media
Great report from Finnish researchers @FICEBO from @MaryanneDemasi
@GuyattGH @shamteppo @finland @thisisFINLAND @FinlandinEU @Pure_Physio @PhysioNetwork @clinthorp @E4Dca @BMJ_EBM @CebmOxford @Clin_Med @EricTopol @VPrasadMDMPH
R to @MaryanneDemasi: Although it’s keyhole surgery — relatively low risk, with a typically quick recovery — it still involves a general anaesthetic. That means small risks that need to be weighed against a procedure that is unlikely to deliver meaningful benefit.
LINK: https://blog.maryannedemasi.com/p/ask-yourself-do-you-really-need-surgery
@kacdnp91 @MaryBowdenMD @Fynnderella1
RFK Jr and the MAHA folks may have inverted the food guide pyramid, turning red meat and full-fat dairy back into health foods, but the @American_Heart is doubling down on the low-fat, plant-based advice it's been disseminating for decades.
Should we expect anything different from the organization that created the low-fat consensus 60+ years ago?
My latest Substack discusses the "one of us stinks" problem caused by challenging consensus science.
It also answers the question raised last week by @MaryanneDemasi, why won't the lipid hypothesis die?
The "One of Us Stinks" Problem: LDL, the Lipid Hypothesis, the AHA, and Humphrey Bogart https://open.substack.com/pub/uncertaintyprinciples/p/the-one-of-us-stinks-problem-ldl?r=7dnq6&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
Abandon the injured trial participants... lose all future recruits.
Low enrollment? Gee I wonder why?
Please read if you have school age children.
But modified mRNA has never been in our food (until now).
Never has modified mRNA ever been introduced into cells using LNPs bypassing natural defenses.
And never has any cell ever made a long lasting pseudouridine modified mRNA to the spike gene.
Not ever.
The mRNA vaccines are NOT traditional messenger RNA- as a chemist you should know better.
There is some misinformation in this @sciam article👇
1- “Extensive research has shown that the snippet of mRNA enters cells but not the cell nucleus” — there is no nucleus during mitosis of dividing cells and so cytoplasmic material mixes with the chromosomes.
2- “mRNA is easily broken down by the body. Humans ingest mRNA all the time from the food we eat, but our digestive system deactivates it” — the mRNA vaccines use pseudouridine-modified mRNA to stabilize the RNA so it isn’t broken down easily. That was a breakthrough that won the Nobel Prize a few years ago. However, it also meant that with the mRNA vaccines, the dose, biodistribution, and persistence in the human body were unknown and have not yet controlled.
3- Data emerged for persistence of COVID mRNA vaccines for over 2 years, not a few hours or days as stated “the mRNA remains for hours or, at most, a few days before a specialized enzyme breaks it down.”
4- The COVID mRNA vaccine “side effects are short-lived and far less serious than an infection,” is inaccurate when one considers numerous side effects such as myocarditis, coagulopathy, neuro-inflammation among others. Post-vaccine syndrome and long-Covid have much in common.
5- “some evidence suggests having more side effects may be associated with a stronger immune response” is misleading as after 4 shots there is IgG4 class switching that has been associated with worse outcomes. For patients with cancer, COVID mRNA vaccination increases PD-L1 expression which is an immune evasion mechanism that is tumor-promoting. While there is some evidence that subsequent treatment with cancer immunotherapy holds promise, the underlying mechanism of synergy can be induced by other agents that actually have anti-tumor efficacy. mRNA vaccines on their own do not have anti-tumor efficacy and the increase in PD-L1 they cause in existing cancers is tumor promoting.
6- “mRNA vaccine technology can speed up vaccine development—as it did with the COVID vaccines” was true in a public health emergency. But corners were cut with a change in the manufacturing process between the original that was tested in clinical trials and what was rolled out globally. Impurities have been found with the use of Process 2 including DNA fragments and plasmid DNA that contains SV40 promoter/enhancer sequences. Assays of DNA contamination that were used have been shown to underestimate contamination due to RNA:DNA hybrids.
There has not been informed consent or liability for mRNA vaccines despite much that has been reported.
It is clear that individuals have varying risk towards any illness and so 6 years later, paying attention to individualized risk and personalized recommendations makes sense. More studies documenting forensic evidence in those with adverse outcomes is needed along with more basic research to further investigate disease mechanisms.
I have written about the need for informed consent from the point of view of cancer risk. It doesn’t mean the risk is high or that anyone whose physician feels would benefit from a COVID mRNA vaccine shouldn’t get it and have it covered by insurance.
I have also written with my colleague @KUPERWASSERLAB a review of COVID infection, COVID vaccines and cancer signals.
There should be a balance in informing the public that I found lopsided in this article.
@HHSGov @US_FDA @NIHDirector_Jay @DrMakaryFDA @SenRonJohnson @Kevin_McKernan @SabinehazanMD @MaryanneDemasi @danaparish @Jikkyleaks @P_McCulloughMD
Why you should keep getting mRNA vaccines
https://www.scientificamerican.com/article/how-do-mrna-vaccines-work-and-why-are-they-safe-and-effective/
R to @MaryanneDemasi: It is unclear how - or if - ACIP will be reconstituted following the legal challenges, or whether any version of the committee under a revised charter could function as an independent advisory body.
https://blog.maryannedemasi.com/p/malone-lifts-lid-on-acip-turmoil
Why won’t the lipid hypothesis die?, by @MaryanneDemasi https://open.substack.com/pub/maryannedemasi/p/why-wont-the-lipid-hypothesis-die?utm_campaign=post-expanded-share&utm_medium=web
R to @MaryanneDemasi: Convincing people to drive their cholesterol levels towards zero is, frankly, bonkers.
https://blog.maryannedemasi.com/p/why-wont-the-lipid-hypothesis-die
⚡️Why won’t the lipid hypothesis die?
Cholesterol guidelines have become more aggressive over time — even as contradictory evidence has accumulated.
So how does this square with the new US guidelines on lipid management?
LINK BELOW 👇👇
@MaryBowdenMD @DrEades @garytaubes @FructoseNo @DrJulieSladden @malcolmken
Another exclusive from @MaryanneDemasi
This time the #plasmidgate cover up at ACIP that required the full force of pharma through its proxy the @AmerAcadPeds to stop this information being presented to public in an official forum.
Why are they so desperate to stop it?
R to @MaryanneDemasi: .@KUPERWASSERLAB lays out a series of unresolved questions — the kinds of questions ACIP meetings are meant to probe. Instead, the meeting was cancelled—and the scrutiny never happened.
LINK: https://blog.maryannedemasi.com/p/the-presentation-acip-never-heard
@MaryBowdenMD @NVICLoeDown
🛑 The presentation ACIP never heard🛑
Here is an exclusive look at the briefing slides by @KUPERWASSERLAB that were never presented to ACIP—and have not been made public until now.
LINK below 👇👇
@jeffreytucker @RetsefL @KMilhoanMDPhD @React19org @BrianneDressen @shdegaray73
@NIHDirector_Jay @SecKennedy
It took the @CDCgov several months to update its vaccine information statements based on ACIP recommendations—and it still hasn’t—but managed to update its website within 5 minutes of this week’s ruling overturning those same recommendations.
CDC has taken down ACIP recommendations from the Sept 18-19, 2025 and Dec 4-5, 2025 meetings where COVID and Hep B shots in babies were moved from "recommended" to "shared clinical decision making."
Additionally, the recommendation that MMRV shots be separated to MMR + V in children under 4 is now gone.
This is a naked power play by Pharma via AAP and an activist judge to neutralize @SecKennedy and restore the full childhood vaccine schedule and the multi billions of dollars it generates. HHS must appeal and reverse this tyrannical decision, with strong presidential backing. Unelected judges cannot be allowed to control the executive branch, elected by the people. @POTUS
R to @MaryanneDemasi: “Unless officially announced by us, any assertions about what we are doing next is baseless speculation,” said HHS spokesperson @AndrewNixonHHS
https://blog.maryannedemasi.com/p/acip-thrown-into-turmoil-as-questions
🚨ACIP thrown into turmoil as questions mount over what comes next
A claim that ACIP has been “disbanded” has sparked confusion — with officials dismissing speculation and offering no confirmed path forward.
LINK BELOW 👇👇
@AndrewNixonHHS @SecKennedy @NIHDirector_Jay