Thank you Akiko for a super illuminating talk filled with night science moments and wonder!
🇩🇪 Übersetzung
RT von @VirusesImmunity: Vielen Dank, Akiko, für einen super aufschlussreichen Vortrag voller nächtlicher wissenschaftlicher Momente und Wunder!
Here is my talk on how studying viral infections can teach us a lot about the immune system, and how we can use those insights to develop vaccines against viruses. "Night science moments" make science so exciting 🌓 @NightScienceIns @ItaiYanai
https://cassyni.com/events/HjViw2SaueSy1e9XCzazYV
🇩🇪 Übersetzung
Hier ist mein Vortrag darüber, wie uns die Untersuchung von Virusinfektionen viel über das Immunsystem lehren kann und wie wir diese Erkenntnisse nutzen können, um Impfstoffe gegen Viren zu entwickeln. „Nachtwissenschaftliche Momente“ machen die Wissenschaft so spannend 🌓 @NightScienceIns @ItaiYanai
https://cassyni.com/events/HjViw2SaueSy1e9XCzazYV
Hey @JacobTref,
Congratulations on stepping into your new role tackling some of the hardest problems in medicine.
There is one condition I strongly encourage you to put on your radar early: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS).
ME/CFS is one of the most severe and neglected chronic diseases that is not rare. In its worst forms, patients are completely bedridden, unable to tolerate light, sound, or human interaction. Quality of life is among the lowest of any illness.
Despite all this, research funding has historically been extremely low relative to disease burden, largely due to long-standing mischaracterization and bias, including the fact that many patients are women.
ME/CFS sits at the intersection of immunology, neurology, and metabolism, involving complex multi-system dysfunction. This is exactly the kind of problem where AI can have an outsized impact by integrating complex data and uncovering hidden leads.
Please take a closer look. Your involvement could make an extraordinary difference to millions affected.
Thank you 🙏
🇩🇪 Übersetzung
RT von @VirusesImmunity: Hallo @JacobTref,
Herzlichen Glückwunsch zu Ihrem Einstieg in Ihre neue Rolle und der Lösung einiger der schwierigsten Probleme in der Medizin.
Es gibt eine Erkrankung, die ich Ihnen dringend empfehlen sollte, frühzeitig auf Ihren Radar zu setzen: Myalgische Enzephalomyelitis / Chronisches Müdigkeitssyndrom (ME/CFS).
ME/CFS ist eine der schwersten und vernachlässigten chronischen Erkrankungen, die nicht selten ist. In den schlimmsten Formen sind die Patienten völlig bettlägerig und nicht in der Lage, Licht, Geräusche oder menschliche Interaktionen zu ertragen. Die Lebensqualität gehört zu den niedrigsten aller Krankheiten.
Trotz alledem war die Forschungsfinanzierung im Verhältnis zur Krankheitslast in der Vergangenheit äußerst gering, was vor allem auf langjährige Fehlcharakterisierungen und Voreingenommenheit zurückzuführen ist, einschließlich der Tatsache, dass es sich bei vielen Patienten um Frauen handelt.
ME/CFS steht an der Schnittstelle von Immunologie, Neurologie und Stoffwechsel und ist mit komplexen Multisystemstörungen verbunden. Dies ist genau die Art von Problem, bei dem KI durch die Integration komplexer Daten und die Aufdeckung versteckter Hinweise einen übergroßen Einfluss haben kann.
Bitte schauen Sie genauer hin. Ihr Engagement könnte für Millionen Betroffene einen außerordentlichen Unterschied machen.
Danke 🙏
Akiko Iwasaki (@VirusesImmunity) is presenting a talk next week in the Night Science Seminar Series on "Insights Gained in the Hunt for Genital Herpes Vaccines". Akiko will discuss both results & the process that led to the discoveries.
Free registration: https://cassyni.com/events/HjViw2SaueSy1e9XCzazYV/abstract
🇩🇪 Übersetzung
RT von @VirusesImmunity: Akiko Iwasaki (@VirusesImmunity) hält nächste Woche einen Vortrag in der Night Science Seminar-Reihe zum Thema „Einblicke bei der Jagd nach Genitalherpes-Impfstoffen“. Akiko wird beide Ergebnisse und den Prozess besprechen, der zu den Entdeckungen führte.
Kostenlose Anmeldung: https://cassyni.com/events/HjViw2SaueSy1e9XCzazYV/abstract
Here is our updated database of grants for early careers researchers in all fields.
It goes way beyond traditional NIH and NSF funding opportunities. We list 428 types of grants.
Download it here: https://research.jhu.edu/rdt/funding-opportunities/early-career/
🇩🇪 Übersetzung
RT von @VirusesImmunity: Hier ist unsere aktualisierte Datenbank mit Stipendien für Nachwuchsforscher in allen Bereichen.
Es geht weit über die traditionellen Finanzierungsmöglichkeiten von NIH und NSF hinaus. Wir listen 428 Arten von Zuschüssen auf.
Laden Sie es hier herunter: https://research.jhu.edu/rdt/funding-opportunities/early-career/
Led by @VirusesImmunity and @KrishnaswamyLab, a team of Yale researchers developed a new tool #Immunostruct that combines multiple types of data to better support the development of personalized vaccines, including vaccines for #cancer.
https://medicine.yale.edu/news-article/using-machine-learning-to-develop-personalized-vaccines-for-cancer/
@SmilowCancer @NatMachIntell
🇩🇪 Übersetzung
RT von @VirusesImmunity: Unter der Leitung von @VirusesImmunity und @KrishnaswamyLab hat ein Team von Yale-Forschern ein neues Tool #Immunostruct entwickelt, das mehrere Arten von Daten kombiniert, um die Entwicklung personalisierter Impfstoffe, einschließlich Impfstoffe gegen #Krebs, besser zu unterstützen.
https://medicine.yale.edu/news-article/using-machine-learning-to-develop-personalized-vaccines-for-cancer/
@SmilowCancer @NatMachIntell
"2025 brachte wichtige Erkenntnisse zu Long Covid, das Rätsel um die Krankheit löst sich langsam. Auch bessere Therapien scheinen möglich."
#LongCovid #MECFS
@VirusesImmunity
https://www.srf.ch/wissen/gesundheit/hoffnung-fuer-betroffene-long-covid-wenn-die-krankheit-endlich-erklaerbar-wird
🇬🇧 Translation
RT by @VirusesImmunity: "2025 brought important insights into Long Covid, the mystery surrounding the disease is slowly being solved. Better therapies also seem possible."
#LongCovid #MECFS
@VirusesImmunity
https://www.srf.ch/wissen/gesundheit/hoffnung-fuer-betroffene-long-covid-wenn-die-krank-endlich-erklaerbar-wird
NYC-area adults with #LongCOVID - you're eligible for a @PutrinoLab @polybioRF clinical trial of sirolimus (rapamycin), with 5 clinic visits over 6mo. Compensation is up to $150; to inquire or enroll, contact CoreResearch@MountSinai.org!
🇩🇪 Übersetzung
RT von @VirusesImmunity: Erwachsene im Raum NYC mit #LongCOVID – Sie haben Anspruch auf eine klinische @PutrinoLab @polybioRF-Studie mit Sirolimus (Rapamycin) mit 5 Klinikbesuchen über 6 Monate. Die Entschädigung beträgt bis zu 150 $; Für Anfragen oder Anmeldungen wenden Sie sich bitte an CoreResearch@MountSinai.org!
Please join us for The Hormone-Immunity Nexus Workshop April 19th at MIT!
A catalyst for a new human-centric research perspective! It's going to be a wonderful workshop bridging Immunology, Gynecology, and Endocrinology through methodological innovation.
https://mit.co1.qualtrics.com/jfe/form/SV_3EN1jNLUEznG8js
Very excited to share our new review in @NatRevImmunol! It was a truly enjoyable and intellectually enriching experience putting this together with @sachinbhag, Stephen and @VirusesImmunity. I hope this reveiw helps move the field of mucosal vaccine research forward :)
A very welcome sober analysis of this incredibly important topic - as expected from this careful group, it captures both optimism and realism "Despite the potential of intranasal vaccines, safety of these approaches must be rigorously tested owing to the anatomical proximity of the nasal mucosa to the central nervous system..."
Very proud of @Kwon_Dongil, @sachinbhag, and Stephen Ehrenzeller for putting together a new review - "Harnessing mucosal immunity for protective vaccines" published today @NatRevImmunol!
Please use the link below to access this review 📖
https://rdcu.be/e4eEU
Review @NatRevImmunol @VirusesImmunity @Yale @Kwon_Dongil @hhmi_science
Harnessing mucosal immunity for protective vaccines
https://www.nature.com/articles/s41577-026-01273-7
Yale School of Medicine researchers review mucosal immunity and find that nasal, oral, and vaginal vaccines can build tissue resident memory T and B cells plus local IgA, blocking infection at entry sites where shots often fall short.
https://www.nature.com/articles/s41577-026-01273-7
Join our study site for the ADDRESS-LC Clinical Trial investigating Bezisterim in Long COVID!
Email: LongCOVIDStudies@yale.edu
https://addresslongcovid.com/
🇩🇪 Übersetzung
RT von @VirusesImmunity: Nehmen Sie an der klinischen ADDRESS-LC-Studie zur Untersuchung von Bezisterim bei Long-COVID auf unserer Studienseite teil!
E-Mail: LongCOVIDStudies@yale.edu
https://addresslongcovid.com/
Too much data, too little thinking.
A important essay from Ruslan Medzhitov on the importance of understanding data, not just generating it. A must read.
@RMedzhitov @YaleIBIO
https://www.nature.com/articles/s41577-026-01276-4
Congratulations to all the immunologists being recognized as Distinguished Fellows of @ImmunologyAAI 👏🏼👏🏼👏🏼
Honored to be a #DFAAI 🙏🏼
See you in Boston #AAI2026
https://www.aai.org/Awards/Career-Awards/Distinguished-Fellows-of-AAI/Current-Recipients
~400M people worldwide have #LongCOVID. Is it appropriate or excessive to routinely wear a close-fitting respirator in public for protection? Prof. Iwasaki @VirusesImmunity said it makes sense to #MaskUp, get boosted and clean the air. Watch the forum: https://masktogetheramerica.org/blog/long-covid-defense-series-ii
Int. ME/CFS Konferenz am 7./8. Mai 2026 in Berlin.
Einreichung wissenschaftlicher Beiträge bis zum 1. März
https://events.mecfs-research.org/de/events/conference_2026
Calling all New Yorkers! If you have #LongCOVID and would like to be a part of this exciting trial exploring low dose rapamycin as a potential therapy, please reach out to the @CoRESinai team. This trial will deepen our understanding of immune dysfunction in LongCOVID. Plz help!
Excellent article examining post-acute infection syndromes (PAIS) across history👏
"While Long COVID is newly defined, PAIS have been described for over a century following epidemic infections [such as] influenza, EBV, & Borrelia burgdorferi..."
Our review is highlighted by the cover of the current issue of @TrendsImmuno -The lingering shadow of epidemics: post-acute sequelae across history by Christine Miller and @jannamoen.
Please read (open access)👇🏼
https://www.cell.com/trends/immunology/fulltext/S1471-4906(25)00267-4
Registration is now open for RTN2026: A 3-day think tank with an outstanding speaker roster. Space is limited — register early! Come ReThink Neuroimmunology with us: https://conferences.weizmann.ac.il/RTN2026/
#RTN2026 #Neuroimmunology
@jonykipnis
@QuintanaLabHMS
@stevens1lab
@RejaneRua
Please help @meighanstone with the housing emergency mentioned below. Like, share, give if you can so she can continue her stellar LC advocacy 🙏 https://www.gofundme.com/f/keep-long-covid-advocacy
Looking forward to participating in this Long COVID defense series II with amazing other guests, Sinéad O'Brien, @betsyladyzhets and @mileswgriffis
As we begin the New Year 2026, I have great hopes for research to advance our understanding of #PAIS. This requires determination and collaboration across fields, sectors, and society. So grateful to work with many of you to find and eliminate root causes of #LongCOVID #MECFS 🙏🏼
(1/n) Just in time for New Years! #ImmunoStruct, our multimodal model that predicts class I peptide-MHC immunogenicity is out at @NatMachIntell !
https://www.nature.com/articles/s42256-025-01163-y
Congratulations to @viccbastos and @KerrieGreene_ for their outstanding work being highlighted in the best of immunology stories 2025 👏🏼👏🏼👏🏼
Original study linked here
https://academic.oup.com/jimmunol/article/214/7/1539/8133211
We are looking for new colleagues in our department! Come and join our vibrant microbiology community! Please RT.