FDA's only honest vaccine regulator was ousted by Moderna, a bunch of biotech investors like Martin Shkreli who bet on the wrong multimillion dollar rare disease drug, FDA bureaucrats who don't want to say no to any vaccines, and a pharma trade press full of people with personal resentment toward a skilled communicator with a biting critique of their terrible COVID reporting.
The final press pile-on that did in Vinay Prasad was that he had the temerity to host a press conference. I thought reporters liked those? I guess not if you're writing for pharma rather than the public.
This has been very clarifying for understanding why people in Vinay Prasad's position in the past have been steamrolled by pharma over and over again. If you say no to the wrong drug, you'll face a massive pressure campaign and termination. Seemingly incomprehensible decisions on Elevidys and Aduhelm suddenly make sense. We're witnessing the counter-example of what happens when the FDA doesn't blink.
I could have talked to @AlexBerenson for much longer than one hour about what it all means, and feel that I personally omitted a lot of critical points. But it's a start, with more to come.
Schmutzkampagne statt Wirtschaftskompetenz
Vor etwa einer Stunde war der Eintritt und die Explosion eines Meteoriten in der Atmosphäre in weiten Teilen West- und Mitteldeutschlands wahrzunehmen. Vielfach wird dabei von einem explosionsartigen Geräusch berichtet. Danke an Angelina Dietz für das Video
“The question is no longer whether we can afford to invest in women's health, but whether we can afford not to.”
Read a new Comment in The Lancet: http://spkl.io/6010AxQXQ
Unfairer Wahlkampf in den letzten Wochen durch die Grünen
Niemand sollte sich zw. aktiver Elternschaft & Politik entscheiden müssen. Deshalb starteten wir vor Jahren fraktionsübergreifend die Initiative Eltern in der Politik: Die Bams sprach darüber mit @schroeder_k, @fbrantner & mir
https://m.bild.de/politik/inland/frauen-allianz-in-der-politik-der-lange-weg-zum-stillraum-im-bundestag-69a99daa2d867e6397075246?t_ref=https%3A%2F%2Fwww.google.com%2F
Für dieses Desaster gibt es für die CDU keine Ausreden. Der „Personenwahlkampf“ von Özdemir wurde erst durch die totale inhaltliche Abwesenheit der CDU möglich gemacht.
Die Wahl des „sympathischeren Kandidaten“ ist die Folge einer depressiven inhaltlichen Einheit und der Abwesenheit irgendeiner Alternative zu Schwarz-Grün.
In Zeiten einer derart dramatischen Wirtschaftslage ist dieses Ergebnis geradezu eine Niederlage für die Demokratie.
https://apollo-news.net/alles-egal-baden-wuerttemberg-zeigt-wie-politik-ohne-inhalte-funktioniert/
Das jährliche 10-Milliarden-Budget der Grünen für Wahlwerbung (und Diffamierung ihrer Gegner) zahlt sich immer wieder aus.
Der Zustand der CDU ist ernst, der von FDP und SPD noch schlimmer.
Phase 2–3 ZSAB-neoGOLP trial: Patients with resectable high-risk intrahepatic cholangiocarcinoma have a high risk of recurrence after surgery. Findings on neoadjuvant GOLP (gemcitabine–oxaliplatin, lenvatinib, and an anti–PD-1 antibody) are summarized in a new Quick Take video. https://www.nejm.org/do/10.1056/NEJMdo008393/full/
Die beste Nachricht des Abends:
Bye, Bye FDP & Strack-Rheinmetall! 👋🏼
Nach dem Sturz des Diktators Bashar al-Asad im Dezember 2024 prallt in Syrien gerade die Theorie der Staatenbildung auf die Realität. Unterwegs mit einem Zollbeamten, Unternehmern und dem obersten Bäcker des Landes. https://www.nzz.ch/folio/1-grenze-sichern-2-geld-drucken3-fladenbrote-vermessen-wie-in-syrien-ein-neuer-staat-entsteht-ld.1919978?utm_campaign=mrf-twitter-NZZ&mrfcid=20260308699bfcf444c4e21fcfd7d072
Die Grünen wirken echt manchmal wie ein parteigewordener Monty-Python-Film
Die Grüne Jugend wirft dem wohl ersten türkeistämmigen Ministerpräsidenten der bundesdeutschen Geschichte wenige Minuten nach dessen Wahlsieg vor, er mache "Politik gegen Migranten". #BadenWürttemberg
Keiner braucht die FDP, weil sie keine liberale Politik macht!
Grausamer Auftritt von Weidel, peinlicher geht nimmer. In jeder Hafenkneipe geht's anständiger zu. Wen soll diese selbstgerechte Scharfrichterattitüde in der konservativen Bürgerschicht eigentlich ansprechen?
Glückwunsch an den (nun sehr wahrscheinlich) nächsten Landesvater @cem_oezdemir.
Die städtischen Regionen haben der Steuerreform zum Durchbruch verholfen. Die grosse Frage ist nun, wie die Kantone reagieren. Für die Mitte-Partei ist es ein schwarzer Tag. https://www.nzz.ch/schweiz/klares-ja-zur-individualbesteuerung-jetzt-beginnt-der-kampf-in-den-kantonen-ld.1927712?utm_campaign=mrf-twitter-NZZ&mrfcid=2026030869aafa01e077e55d2a039331
@mtaibbi You should look into the @VPrasadMDMPH story at FDA. The corruption runs really deep. He tried to reform the agency & break pharma/biotech's control & was immediately met with leaks & appalling personal attacks, along with a media campaign against him...
Tochter und ich sahen diesen Leuchtkörper vom Wohnzimmerfenster aus und rannten spontan auf die Terrasse. Wir dachten wirklich, wir sehen ein UFO.
Schlechte Karten für FDP und SPD in Baden-Württemberg
@VPrasadMDMPH is one of the scarce few truth-tellers in medicine today. He is brilliant, ethical, honest, yes - decisive - and funny. This is a tremendous loss to the FDA and the American public. I do wish Makary or Trup had been able to push back against the corruption.
Vinay once said on a pod during the pandemic - do the work, then step into the ring. He has opinions because he does the work, he knows the data. How many of those who disagree with him have the intellectual honesty (or skill) to even ask the right questions, let alone interpret the data. This is a great loss. I'd be sad longer if I weren't convinced VP would be on to more gratifying endeavors and other pursuits that will continue to elevate the practice of medicine.
Best wishes to you, VP! Can't wait to see what is next.
@anish_koka - absolutely brilliantly written. How in the world do you do it all?!
I have seen some scummy people in my life, but the people on this site pushing UniQure are some of the scummiest I have ever seen. They literally have no shame, although this seems to describe much of biotech. Pushing treatments that don't work, exploiting vulnerable people.
Viele Augenzeugen berichten dem WDR, dass über Teile von NRW ein großer, heller Leuchtköper gesehen wurde. Er bewegte sich quer über den Himmel und wurde in Köln und auch im Ruhrgebiet gesehen. Bislang ist unklar, um was es sich gehandelt hat, viele vermuten einen Meteoriten.
Eine Erhebung sah zuletzt die Grünen und die CDU in Baden-Württemberg gleichauf. Es dürfte ein enges Kopf-an-Kopf-Rennen werden. Die neuesten Entwicklungen im Live-Ticker. https://www.nzz.ch/international/landtagswahl-baden-wuerttemberg-cdu-und-gruene-kaempfen-um-die-staatskanzlei-ld.1928052?utm_campaign=mrf-twitter-NZZ&mrfcid=2026030869aafa01e077e55d2a039330
Knallhart Grün - Schlechte Nachrichten für Baden-Württemberg
Der schleichende Abgang des Mittelstandes und die Wahl in Baden-Württemberg
Das Wahlergebnis in Baden-Württemberg verstärkt den ökonomischen Abwärtstrend.
Nova survivor Yuval Sharvit:
"The girl who was injured in the car next to me was dragged out by the terrorists. She begged the person in the car with her to help her, but he was trapped. She started screaming that they were ripping her clothes off. There were three terrorists. They raped her. I've never heard screams like that in my life, and the terrorists sounded like they were drinking a cocktail at the beach. When they finished, they fired an RPG at her car and burned her. After everything she went through, she was burned alive."
@grok: I want to know why there isn't a single pediatric practice in the world where the rate of sudden onset autism (the parents observe the child literally goes from normal to behaviors consistent with ASD) is greater in the week BEFORE the vaccine appointment vs. in the week AFTER the vaccine appointment. It isn't ascertainment bias since the physician is much more likely to hear about the regression if it happened right before the visit rather than after since the parent will walk in and tell the doctor at the visit; no need for the parent to do a call into the doctor (who are always hard to reach). I know of one pediatrician where the numbers were 0 before and 44 cases within a week after the visit (Doug Hulsteadt). Surely, half the pediatric practices are seeing opposite numbers because we all know vaccines don't cause autism, irght? So why is everyone unable to identify a single clinic where the BEFORE visit rates are > than the AFTER visit rates. Also in Hulstedt's practice, 0 and 44... the statistical chance of that happening is 1 in 2e13 which seems impossible if there is no causality and this is random chance, right? So this should be documented as THE SINGLE BIGGEST coincidence in medical history, right? And why do all the scientists REFUSED to study this by DELIBERATELY lumping in the slow onset cases with the rapid onset cases, rather than doing the subgroup analysis on the rapid onset cases? By lumping them together, they OBSCURE the signal of the rapid onset cases. They will not do the subgroup analysis and they will NOT make the data publicly available. So the science isn't settled because they are avoiding the subgroup analysis that would tell us the answer. I wonder why. They have the data, but they simply make sure to bury the needle in the haystack, don't they?
let me introduce you to CRISPR
Wahlergebnis #Schützingen (Zweitstimmen; ohne Gewähr!):
Die Grünen: 75 Stimmen
CDU: 99
SPD: 16
FDP: 18
AfD: 111
Die Linke: 6
Tierschutzpartei: 5
Sonstige: Zwischen 0 und 3
#BadenWürttemberg
#BadenWürttembergWahl2026
R to @FrankfurtZack: Mutter, Ehefrauen, Töchter alle natürlich kopftuchlos. So wie es ja eigentlich auch vor paar Jahrzehnten ganz normal war.
French not only argues that Talarico shines as “decent,” he says Talarico shows what it looks to be “kind” on the campaign trail. Think about that, this man advocates for the murder of the unborn and the most extreme forms of perversion.
Yet French finds him a decent and kind public example of Christianity as if all Christ requires is that we say things in a Mr. Rogers cadence and vocabulary.
This is why it’s so important to remember what Romans 16:18 tells us about what false teachers looks like. They will fool the naïve through smooth talk and flattery. Such qualities are rarely perceived as abrasive or offensive.
Scripture tells you to run from men like this. French tells you to embrace him.
Bin kein Freund der Grünen, aber für den zunehmenden Islamismus im Land ist jemand wie Cem Özdemir natürlich ein echter Schlag in die Fresse.
In dem Punkt wird das spannend.
1/2
Journal of the Royal Statistical Society
Some statistical aspects of the Covid-19 response
Einige statistische Aspekte der Covid-19–Maßnahmen
Simon N Wood and others
https://academic.oup.com/jrsssa/article/189/1/1/8180652
Abstract:
Dieser Artikel beleuchtet einige statistische Aspekte der britischen
Rooney says that standing up for Palestine is part of a bigger fight against tech, finance, and the fossil fuel industry who threaten our existence.
Totally incoherent gibberish. People have lost the ability to think and speak.
Vom klaren Favoriten zum Zweitplatzierten hinter den #Oezdemir -Grünen: Für die baden-württembergischen #CDU ist dieser Wahlausgang mehr als nur schmerzhaft. Zumal die #AfD sehr stark abschneidet. Die Atmosphäre ist vergiftet. Wie kann es jetzt weitergehen? #Hagel #Wahlsieger
https://www.cicero.de/innenpolitik/landtagswahl-in-baden-wurttemberg-das-brutale-debakel-der-hagel-cdu
News by @corajamine: A senior figure in Iran’s Kurdish opposition has tied any potential ground incursion into Iran to a major U.S. military decision: the establishment of a no-fly zone over Kurdish areas in western Iran. https://www.politico.com/news/2026/03/08/kurdish-no-fly-zone-00818314