Impf_Info – Following Feed 25,919 Posts (gefiltert)

R to @apsmunro: The wording on antibiotic timing has been updated The last version already introduced a longer window for antibiotic administration to enable time to establish diagnosis - this update emphasises using this time to investigate This bit is key... 3/

R to @apsmunro: Sepsis screening in children has, IMO, been a debacle Tools perform extremely poorly and are frequently felt to cause more harm than good @Damian_Roland and I have argued for some time this process needs completely rethinking 3/ https://www.bmj.com/content/381/bmj.p1327.long

R to @apsmunro: First the good news The guidelines have REMOVED the recommendation to institute sepsis screening The evidence is too muddy to demonstrate this is worthwhile This has been supplemented by "recommending" hospitals institute quality improvement programs 2/

The new surviving sepsis guidelines are out The adult guidelines are already taking a battering (including ACEP refusing to endorse 😬) The paediatric guidelines are actually more interesting Some thoughts 1/ https://journals.lww.com/pccmjournal/fulltext/9900/surviving_sepsis_campaign_international_guidelines.651.aspx

Pinned: Liebe Hörer, am 20. Juni feiern wir wieder unseren Geburtstag und was wäre unsere Geburtstagsfeier ohne Sie, unsere treuen Hörer und Unterstützer! Kommen Sie ins Congress Center Würzburg und feiern Sie mit uns. Tickets zur Veranstaltung gibt es ab sofort hier: https://eventfrog.de/kontrafunk4 Wir freuen uns auf Sie!

R to @ClareCraigPath: gov.uk/drug-safety-update/fl…

Ciprofloxacin should not be given to healthy people. Here is government guidance:

Präsident Trump hat langjährige Sanktionen gegen den Kriegsgegner Iran aufgehoben. Das zeigt, wie stark der wirtschaftliche Druck auf das Weisse Haus durch die steigenden Ölpreise inzwischen geworden ist. https://www.nzz.ch/meinung/mit-der-lockerung-der-oelsanktionen-gegen-teheran-bestaetigt-trump-die-groesste-schwachstelle-der-usa-ld.1930583?utm_campaign=mrf-twitter-NZZ&mrfcid=2026032469c01201793f935293a8b374

"Die Schweiz hat ein Problem mit Kriminalität. Und das heisst vor allem: mit Ausländerkriminalität. Von 90 000 registrierten Straftaten gemäss Strafgesetzbuch werden nur rund 40 Prozent von Schweizern begangen." https://www.nzz.ch/meinung/die-schweiz-hat-ein-problem-mit-importierter-gewalt-doch-die-realitaet-wird-ignoriert-ld.1930573

"This is how they end informed consent, forever." @brownstoneinst @jeffreytucker https://www.youtube.com/watch?v=XkSgrnValj0&t=22s

R to @orwell2022: No hockey sticks in the historic USCRN sites. Is it the reason why they don’t show it nor talk about it? They probably looked. Because they designed it in order to have places with history. With controlled station upgrade. But the data didn’t show what they hoped to see?

Virologin Prof. Karin Moelling: "Das, was im Moment gemacht wird, ist zu viel, ist zu streng (…) und von Angst getrieben (…) wir haben keine hohe Sterbe- und Krankheitsrate, und die Krankheit verläuft relativ milde. Das sollte man sich klarmachen." 17.03.2020 #RichtigErinnern

Für Magnete in E-Autos oder in Windrädern sind Seltene Erden nötig. Ihr Abbau in oft unregulierten Minen in Südostasien vergiftet Flüsse und Menschen. Eine Umweltkatastrophe, die Abermillionen von Menschen, Tieren und Pflanzen betreffen kann. https://www.infosperber.ch/wirtschaft/uebriges-wirtschaft/wie-der-abbau-von-seltenen-erden-suedostasien-vergiftet/ Bildquelle: © Basile Morin, Wikimedia Commons

I wrote the articles and the soundtrack. May I present: Nicole Junkermann 👇

🔴 Für Millionen Autofahrer könnte es bald teurer werden: Der ADAC will seine Mitgliedsbeiträge kräftig anheben, wie WELT erfuhr. Intern ist der Schritt nicht unumstritten. https://www.welt.de/wirtschaft/plus69c2647fd8eccf8272e7e43e/automobilclub-adac-plant-groesste-beitragserhoehung-seiner-geschichte.html

She's bang on.

NINE DEAD BABIES for every neural tube defect "prevented". 9⃣🪦👶 And they call it "public health". Link in next tweet.

R to @ClareCraigPath: hartuk.substack.com/p/six-sa…

Needless to say, if congressmembers didn’t get a special expedited security process the TSA debacle we’ve been dealing with for years, let alone the current situation, would never have happened. Delta’s revocation should be permanent.

Also right on time. Boy, these bastards are really going for it this time, aren't they.

We spent hours talking to Greg Bovino in his final days as a Border Patrol official. He mocked Tom Homan. Criticized the current CBP chief. Acknowledged clashes with ICE and the National Guard. Lots more here: https://www.nytimes.com/2026/03/24/us/gregory-bovino-border-patrol.html

I have some words to describe how this makes me feel but I can't write them here.

Bei der Landtagswahl in Rheinland-Pfalz hat die SPD erneut eine herbe Niederlage erlitten. Im Bund sind ihre Umfragewerte schon länger schlecht. Wie ist das zu erklären? https://www.nzz.ch/international/krise-der-spd-warum-verliert-die-einstige-volkspartei-so-viele-waehler-ld.1930574?utm_campaign=mrf-twitter-NZZ&mrfcid=2026032469c01201793f935293a8b373

R to @orwell2022: Background. Those are the sites added. To the https://orwell2024.github.io/builtmap/ tool.

Feature update: Added the historical USCRN sites to the map. Those locations have the highest integrity and quality data.

One year to fatten the wallets. Say goodbye to the tourism industry/travel if people don't pitch in to stop this madness.

in Berlin ist eine Parallelgesellschaft entstanden, die dem ganzen Land weit mehr Schaden als Nutzen bringt.

wow

The U.S. government invests over $21 billion annually in Graduate Medical Education (GME) to support ACGME-accredited training, primarily through Medicare. Medicare provides the majority of funding, averaging $112,000–$129,000 per resident annually, with additional funding from Medicaid and the VA. ~2 out of 3 American applicants to medical school don’t get in. Given that medical schools have actively been discriminating against white and Asian citizens because of explicitly racist affirmative action policies, there are likely to be a fair number of perfectly capable American citizens who want to be doctors that don’t make it through the process. Hospitals sees medical trainees as cash cows - federally funded labor — they dont care where you were born. It’s yet another nice arbitrage for your friendly non-profit that may be advertising in the next Super Bowl while sending uninsured patients to collections. We need accelerated pipelines for American citizens to practice medicine. But as long as there is a constant supply of foreign medical graduates which hospitals are cashing in on, nothing will change.

Tuberculosis remains a leading cause of death worldwide among persons with HIV. In this report, the effect of the PEPFAR program on incident cases of tuberculosis and related deaths is presented. Read the full report: https://www.nejm.org/doi/full/10.1056/NEJMc2506284 @CDCgov | #WorldTBDay

I don’t have a dog in the fight when it comes to the next leader of Iran. I just don’t want it to be an Islamist who wants to murder Americans.

Meningitis outbreak WAS caused by a new variant with significant mutations that are likely to have impacted on how fast it spread, officials say https://trib.al/FB9jDfs

Front page of IRGC's Tasnim newspaper today: “Coward Loser of the Game” 👇 They will find out soon who is the loser... _

Volume 5 Issue 4 of 𝘕𝘌𝘑𝘔 𝘌𝘷𝘪𝘥𝘦𝘯𝘤𝘦 is now available! Here is a preview of the latest content: 𝗣𝘂𝗯𝗹𝗶𝗰 𝗛𝗲𝗮𝗹𝘁𝗵 𝗔𝗹𝗲𝗿𝘁𝘀 Multistate Infant Botulism Outbreak Associated with Powdered Infant Formula https://eviden.cc/4qXflB5

Celebrating the draft FDA Bayesian guidance document with our perspective in @JAMA_current. Honored to co-author with Jack Lee (MD Anderson), Lisa LaVange (past director of Office of Biostatistics FDA CDER and president of ASA @AmstatNews ),& my Bayesian inspiration @d_spiegel

Worth pointing out that the vaccination program cannot possibly be credited with the fall in cases - immunity not evident until a couple of weeks after the second dose.

A deep trawl on how to make the worst product safety signals in history go away https://www.bmj.com/content/372/bmj.n810/rr-28 5 years later we are supposed honour studies that show infinitesimal effects. Anyone fancy an Epstein style massage? @sayerjigmi

Nach acht Jahren Verhandlungen steht das Freihandelsabkommen zwischen Canberra und Brüssel. Es öffnet Märkte und setzt ein politisches Signal gegen Protektionismus. https://www.nzz.ch/wirtschaft/freihandel-in-unsicheren-zeiten-eu-und-australien-besiegeln-ihren-mega-deal-ld.1930704?utm_campaign=mrf-twitter-NZZ&mrfcid=2026032469c01201793f935293a8b372

Woah.

In the 19th century, “humanized lymph” was the standard method of propagating the smallpox vaccine. It involved taking pustular (pus!) material (lymph) from the vaccine sore of a vaccinated person and transferring it directly to the arm of another person —typically after the recipient’s arm had been scored with a lancet. For much of the century, this method of arm-to-arm vaccination was the primary means of administering the vaccine. No hypodermic needle. No sterilization of the site. Often, there was no clear understanding of the material’s precise origin—whether it derived from cowpox, horsepox, goat, or someone suffering or who died with smallpox.) Does this sound like science to you? “...children and adults comparatively recently vaccinated with humanized lymph, and some showing good marks, may subsequently, within few days, months, or years, contract smallpox is an undoubted fact, known to all of us. I have myself recorded 469 cases of persons, of all ages and both sexes, suffering from smallpox after vaccination, with 99 deaths — an average of 21 per cent.; and higher figures are given by Dr. Collie. Now, many of these sufferers showed good vaccine marks of the kind that would be deemed worthy of an extra grant from the Government-Inspector (at least, I used formerly to receive such grants for doing similar work); and yet they took smallpox-some within six days, some within six months, and some within six years of vaccination.” — Dr. Browning, the Medical Officer of Health for Rotherhithe, London [George William Winterburn, PhD, MD, The Value of Vaccination: A Non-partisan Review of Its History and Results, 1886, pp. 75–76.]